How Common Medications Can Affect Your Weight

Dr. Bilkisu Gaye

Do you know that some of the medications you’re taking could be impacting your weight? Whether it's a positive or negative effect, understanding how your medications influence your body can be crucial, especially if you’re trying to manage your weight. Here’s a closer look at how different types of medications can affect your weight.



Diabetes Medications


For those managing diabetes, certain medications can actually help with weight loss, which not only benefits diabetes management but also reduces the risk of heart disease. The preferred medications include:

  • Metformin
  • GLP-1 Agonists (medications ending in "-glutide" like semaglutide)
  • SGLT-2 Inhibitors (medications ending in "-gliflozin")
  • Pramlintide
  • Acarbose
  • DPP-4 Inhibitors (medications ending in "-gliptin")


These medications are often favored because they can aid in weight loss. On the other hand, medications such as insulin, sulfonylureas (like glipizide), glitazones, and meglitinides are known to cause weight gain. If you’re taking any of these, it might be worth discussing alternatives with your doctor.



Hypertension Medications


When it comes to managing high blood pressure (hypertension), some medications are weight-neutral or even promote weight loss. Preferred options include:

  • ACE Inhibitors (medications ending in "-pril," like lisinopril)
  • ARBs (medications ending in "-sartan," like valsartan)
  • Thiazide Diuretics (such as hydrochlorothiazide)


These medications are less likely to interfere with your weight loss goals. However, if you’re on selective beta-blockers (like metoprolol or carvedilol), calcium channel blockers (like nifedipine or amlodipine), or alpha-blockers (like prazosin), be aware that these can contribute to weight gain. If weight loss is a goal, you might want to explore alternative treatments with your healthcare provider.



Antihistamines


If you suffer from allergies, the type of antihistamine you choose can also impact your weight. The following medications are preferred because they are less likely to cause weight gain:

  • Cetirizine (ZyrTEC)
  • Fexofenadine (Allegra)
  • Loratadine (Claritin)

In contrast, antihistamines such as diphenhydramine (Benadryl) and cyproheptadine (Periactin) can lead to weight gain, so avoiding these when possible is advisable.



Contraception


When it comes to birth control, many forms are weight-neutral, meaning they don't significantly affect your weight. These include:

  • IUDs
  • NuvaRing
  • Oral Contraceptive Pills (OCPs)

However, Depo-medroxyprogesterone (Depo-Provera) is known to cause weight gain, so it’s something to consider if you’re trying to maintain or lose weight.



Comprehensive Weight Loss Programs at Designed4Wellness


At Designed4Wellness, we offer comprehensive, physician-led weight loss programs where your physician understands the crucial link between the medications you’re taking and how they can affect your weight loss goals. Our providers conduct a thorough review of your current medications before prescribing any new ones, ensuring that every aspect of your treatment supports your weight loss journey. We believe in a personalized approach to weight management, integrating medication review as a general part of our comprehensive weight loss programs.



Conclusion


Understanding the potential effects of medications on your weight is important for managing your overall health. If you’re concerned about how your medications might be influencing your weight, talk to your healthcare provider. At Designed4Wellness, we’re here to help you find the best treatment plan that aligns with your health goals, including weight management.



Share this post if you found it helpful and subscribe to our blog for more tips on health and wellness. Subscribers get a free infographic on our 10 + 20 program for lifestyle and longevity reset and receive notifications for free webinars. Text us on WhatsApp for more details.

Subscribe to our food and health blogs

* indicates required

Please share ....

Artificial Sweeteners
By Dr. Bilkisu Gaye March 7, 2025
Artificial sweeteners may have zero calories, but that doesn’t mean they’re good for you. Some people love Diet Coke, others hate it, but most don’t realize that these zero-calorie drinks do not help with weight loss
By Dr. Bilkisu Gaye February 28, 2025
Polycystic Ovary Syndrome (PCOS) is a complex hormonal disorder that affects millions of women worldwide. It is a leading cause of infertility and is often associated with insulin resistance, irregular menstrual cycles, and an increased risk of developing type 2 diabetes and cardiovascular disease.
By Dr. Bilkisu Gaye January 10, 2025
When discussing hunger and its impact on mental and physical health, it's essential to recognize the complex pathways involved in regulating appetite. These pathways, coupled with societal and psychological influences, can significantly impact overall health. At Designed4Wellness, our 10 + 20 program emphasizes the three pillars of nutrition, exercise, and stress reduction to address these intricacies.